HSS178992

• Gene Symbol: DROSHA
• Gene Name: drosha ribonuclease III
• Gene Aliases: ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L, RNASEN
• Chromosome Location: Chr.5: 31400494 - 31532175 on Build GRCh38
• UniGene ID: Hs.97997
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DROSHA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001100412.1	NP_001093882.1	24, 25	3372
	NM_013235.4	NP_037367.3	24, 25	3407
	XM_005248291.3	XP_005248348.1	25, 26	3483
	XM_005248292.3	XP_005248349.1	25, 26	3459
	XM_005248293.3	XP_005248350.1	24, 25	3390
	XM_005248294.3	XP_005248351.1	23, 24	3279
	XM_011514033.2	XP_011512335.1	25, 26	3483
	XM_017009399.1	XP_016864888.1	24, 25	3366
	XM_017009400.1	XP_016864889.1	24, 25	3348
	XM_017009401.1	XP_016864890.1	23, 24	3255
	XM_017009402.1	XP_016864891.1	13, 14	1498
GenBank mRNA	AF116910.1	-	9, 10	936
	AK001121.1	-	13, 14	1242
	AK026563.1	-	4, 5	294
	AK308093.1	-	23, 24	3181
	BC024261.1	-	12, 13	1168
	BC041162.1	-	11, 12	1093
	BC054003.1	-	23, 24	3184	6148714
	BX647724.1	-	24, 25	3275

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107655, XM_006232049, XM_006232050, FQ215440, FQ212690.
This siRNA also targets the following transcripts in Mouse: NM_001130149, NM_026799, AF533013, BC055696, BC050057, and others.

Gene Ontology Categories:

Process(es)

miRNA metabolic process
positive regulation of gene expression
rRNA catabolic process
production of siRNA involved in RNA interference
gene silencing by RNA
primary miRNA processing
pre-miRNA processing
ribosome biogenesis
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
RNA phosphodiester bond hydrolysis, endonucleolytic
regulation of miRNA metabolic process

Function(s)

lipopolysaccharide binding
double-stranded RNA binding
ribonuclease III activity
protein binding
protein homodimerization activity
poly(A) RNA binding
metal ion binding
primary miRNA binding