HSS181484

• Gene Symbol: NEFL
• Gene Name: neurofilament, light polypeptide
• Gene Aliases: CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110
• Chromosome Location: Chr.8: 24950955 - 24956869 on Build GRCh38
• UniGene ID: Hs.521461
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEFL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006158.4	NP_006149.2	3	1564
GenBank mRNA	AK057731.1	-	4	1138
	AK075003.1	-	3	1307
	AK127430.1	-	5	1007
	AK225975.1	-	3	1307
	AK299095.1	-	4	1149
	AK314591.1	-	3	1307
	AL713644.1	-	4	740
	AY156690.1	-	3	1210
	BC039237.1	-	3	1307	4280159

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
microtubule cytoskeleton organization
anterograde axonal transport
retrograde axonal transport
response to toxic substance
peripheral nervous system axon regeneration
axonal transport of mitochondrion
spinal cord development
hippocampus development
cerebral cortex development
regulation of axon diameter
neurofilament bundle assembly
locomotion
response to peptide hormone
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
intermediate filament polymerization or depolymerization
intermediate filament organization
neuron projection morphogenesis
positive regulation of axonogenesis
neuromuscular process controlling balance
protein polymerization
response to corticosterone
response to sodium arsenite
response to acrylamide

Function(s)

Ras guanyl-nucleotide exchange factor activity
structural constituent of cytoskeleton
protein binding
protein C-terminus binding
protein domain specific binding
protein binding, bridging
identical protein binding
phospholipase binding
protein heterodimerization activity