HSS182673

• Gene Symbol: APTX
• Gene Name: aprataxin
• Gene Aliases: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
• Chromosome Location: Chr.9: 32883872 - 33025129 on Build GRCh38
• UniGene ID: Hs.20158
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APTX
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001195248.1	NP_001182177.1	7	867
	NM_001195249.1	NP_001182178.1	7	1036
	NM_001195250.1	NP_001182179.1	6	705
	NM_001195251.1	NP_001182180.1	8	973
	NM_001195252.1	NP_001182181.1	7	651
	NM_001195254.1	NP_001182183.1	6	727
	NM_175069.2	NP_778239.1	7	867
	NM_175073.2	NP_778243.1	8	973
	NR_036576.1		7	862
	NR_036577.1		7	752
	NR_036578.1		7	884
	NR_036579.1		7	1031
	XM_006716791.3	XP_006716854.1	7	875
	XM_006716792.2	XP_006716855.1	7	893
	XM_011517938.1	XP_011516240.1	6	851
	XM_011517939.2	XP_011516241.1	6	806
	XM_017014837.1	XP_016870326.1	6	956
	XM_017014838.1	XP_016870327.1	7	849
GenBank mRNA	AB603741.1	-	6	763
	AK000164.1	-	6	870
	AK055672.1	-	7	854
	AK131046.1	-	7	819
	AY040777.1	-	7	842
	AY208829.1	-	7	842
	AY208830.1	-	6	705
	AY208831.1	-	7	617
	AY208832.1	-	6	680
	AY208833.1	-	6	680
	AY208834.1	-	6	781
	AY208835.1	-	7	822
	AY208836.1	-	7	982
	AY208837.1	-	8	939
	AY208838.1	-	6	798
	AY208839.1	-	7	976
	AY208840.1	-	7	839
	AY208841.1	-	6	676
	AY208842.1	-	4	476
	AY302067.1	-	6	985
	AY302068.1	-	6	980
	AY302069.1	-	6	870
	AY302070.1	-	6	865
	AY302071.1	-	5	758
	AY302072.1	-	5	753
	AY302073.1	-	5	643
	AY302074.1	-	5	638
	BC001628.1	-	6	690
	BC032650.1	-	7	908	5505120
	BC068107.1	-	8	948
	BC104881.1	-	7	881	8143884
	BX538161.1	-	8	952

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_148889, XM_008763607, XM_006238028, XM_006238027, XM_006238026, and others.
This siRNA also targets the following transcripts in Mouse: NM_001025444, NM_025545, NM_001025445, BC068309, BC071213, and others.

Gene Ontology Categories:

Process(es)

single strand break repair
DNA ligation
cellular response to DNA damage stimulus
dephosphorylation
regulation of protein stability
response to hydrogen peroxide
nucleic acid phosphodiester bond hydrolysis

Function(s)

chromatin binding
damaged DNA binding
double-stranded DNA binding
double-stranded RNA binding
protein binding
phosphoglycolate phosphatase activity
DNA 5'-adenosine monophosphate hydrolase activity
metal ion binding
protein N-terminus binding
phosphoprotein binding