HSS188722

Gene Symbol:

KLRC4 KLRC4-KLRK1

Gene Name:

killer cell lectin like receptor C4

KLRC4-KLRK1 readthrough

Gene Aliases:

NKG2-F, NKG2F

-

Chromosome Location:

Chr.12: 10407384 - 10409757 on Build GRCh38

Chromosome Location:

Chr.12: 10372353 - 10410146 on Build GRCh38

UniGene ID:

Hs.721094

Hs.387787

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: KLRC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013431.2	NP_038459.1	4	643
GenBank mRNA	AF350018.1	-	4	461
	AF350019.1	-	4	461
	AJ001683.1	-	4	643
	BC017784.1	-	4	475	4619154
	U96845.1	-	4	493

Gene Symbol: KLRC4-KLRK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199805.1	NP_001186734.1	4	322
GenBank mRNA	AF461811.1	-	4	331
	AK292020.1	-	4	435
	AK310717.1	-	4	435
	X54870.1	-	1	98

More Information

Gene Ontology Categories:

Process(es)

cellular defense response
stimulatory C-type lectin receptor signaling pathway
adaptive immune response
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
signal transduction
natural killer cell activation
cell differentiation
positive regulation of myeloid dendritic cell activation
T cell costimulation
positive regulation of interferon-gamma production
negative regulation of GTPase activity
positive regulation of apoptotic process
innate immune response
positive regulation of nitric oxide biosynthetic process
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
defense response to Gram-positive bacterium
cellular response to lipopolysaccharide
negative regulation of natural killer cell chemotaxis

Function(s)

receptor activity
protein binding
kinase binding
carbohydrate binding
MHC class Ib receptor activity
MHC class I protein binding
protein homodimerization activity