HSS190418

• Gene Symbol: H2AFY
• Gene Name: H2A histone family member Y
• Gene Aliases: H2A.y, H2A/y, H2AF12M, MACROH2A1.1, mH2A1, macroH2A1.2
• Chromosome Location: Chr.5: 135334381 - 135399887 on Build GRCh38
• UniGene ID: Hs.420272
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: H2AFY
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001040158.1	NP_001035248.1	2	253
	NM_004893.2	NP_004884.1	2	216
	NM_138609.2	NP_613075.1	2	253
	NM_138610.2	NP_613258.2	2	253
	XM_005272132.1	XP_005272189.1	2	631
	XM_005272134.3	XP_005272191.1	2	631
	XM_005272135.3	XP_005272192.1	2	631
	XM_011543729.2	XP_011542031.1	2	170
	XM_011543730.2	XP_011542032.1	2	173
	XM_011543731.1	XP_011542033.1	2	631
	XM_011543732.1	XP_011542034.1	2	631
	XM_011543733.2	XP_011542035.1	2	631
	XM_011543734.2	XP_011542036.1	2	631
	XM_011543735.2	XP_011542037.1	2	631
	XM_017010067.1	XP_016865556.1	2	631
	XM_017010068.1	XP_016865557.1	2	631
	XM_017010069.1	XP_016865558.1	2	631
GenBank mRNA	AF044286.1	-	1	45
	AF054174.1	-	2	216
	AK023409.1	-	2	244
	AK296014.1	-	2	244
	AY134746.1	-	1	29
	BC013331.1	-	2	179	4077577
	BC095406.1	-	2	213	30348703
	BE262597.1	-		270

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth
nucleosome assembly
chromatin silencing
dosage compensation
covalent chromatin modification
regulation of lipid metabolic process
negative regulation of histone phosphorylation
positive regulation of maintenance of mitotic sister chromatid cohesion
regulation of gene expression, epigenetic
positive regulation of keratinocyte differentiation
negative regulation of gene expression, epigenetic
positive regulation of gene expression, epigenetic
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K27 methylation
regulation of chromatin silencing at rDNA
establishment of protein localization to chromatin
negative regulation of protein serine/threonine kinase activity
negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
negative regulation of cell cycle G2/M phase transition
negative regulation of protein localization to chromosome, telomeric region

Function(s)

rDNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
protein binding
double-stranded methylated DNA binding
enzyme binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
chromatin DNA binding
nucleosomal DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity