MSS201475

• Gene Symbol: Egln3
• Gene Name: egl-9 family hypoxia-inducible factor 3
• Gene Aliases: 2610021G09Rik, AI505553, AI648162, Hif-p4h-3, Phd3, SM-20
• Chromosome Location: Chr.12: 54178981 - 54203874 on Build GRCm38
• UniGene ID: Mm.133037
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egln3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_028133.2	NP_082409.2	1	355
GenBank mRNA	AF421882.1	-	1	256
	AJ310548.1	-	1	336
	AK033509.1	-	1	283
	AK044787.1	-	1	357
	AK165972.1	-	1	286
	AK170732.1	-	1	286
	BC044926.1	-	1	265	5373240
	BC058278.1	-	1	275	6528802
	BC069893.1	-	1	283	4978765

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019371, U06713.

Gene Ontology Categories:

Process(es)

response to hypoxia
apoptotic process
cellular response to DNA damage stimulus
protein hydroxylation
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
peptidyl-proline hydroxylation
regulation of cell proliferation
regulation of neuron apoptotic process
oxidation-reduction process

Function(s)

iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity
metal ion binding
dioxygenase activity