MSS202310

• Gene Symbol: Axin1
• Gene Name: axin 1
• Gene Aliases: AI316800, Axin, Fu, Kb, Ki, fused, kinky, knobbly
• Chromosome Location: Chr.17: 26130972 - 26195811 on Build GRCm38
• UniGene ID: Mm.23684
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Axin1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001159598.1	NP_001153070.1	2	730
	NM_009733.2	NP_033863.2	2	730
GenBank mRNA	AF009011.1	-	2	682
	BC011544.1	-	2	450
	BC113171.1	-	2	462	40061055

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_024405, AF017756.

Gene Ontology Categories:

Process(es)

protein polyubiquitination
in utero embryonic development
optic placode formation
regulation of protein phosphorylation
positive regulation of protein phosphorylation
nucleocytoplasmic transport
apoptotic process
signal transduction
activation of JUN kinase activity
multicellular organism development
determination of left/right symmetry
sensory perception of sound
adult walking behavior
cell death
dorsal/ventral axis specification
dorsal/ventral pattern formation
Wnt signaling pathway
hemoglobin metabolic process
forebrain anterior/posterior pattern specification
Wnt-activated signaling pathway involved in forebrain neuron fate commitment
cell differentiation
protein catabolic process
negative regulation of Wnt signaling pathway
positive regulation of transforming growth factor beta receptor signaling pathway
olfactory placode formation
cytoplasmic microtubule organization
positive regulation of protein ubiquitination
activation of protein kinase activity
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
erythrocyte homeostasis
negative regulation of transcription elongation from RNA polymerase II promoter
regulation of catenin import into nucleus
post-anal tail morphogenesis
termination of G-protein coupled receptor signaling pathway
positive regulation of JUN kinase activity
positive regulation of GTPase activity
cellular protein complex assembly
negative regulation of fat cell differentiation
positive regulation of protein catabolic process
positive regulation of protein kinase activity
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
embryonic eye morphogenesis
axial mesoderm development
axial mesoderm formation
neurological system process
negative regulation of protein metabolic process
protein homooligomerization
positive regulation of ubiquitin-protein transferase activity
muscle cell development
canonical Wnt signaling pathway
embryonic skeletal joint morphogenesis
canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
cellular response to organic cyclic compound
genetic imprinting
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

p53 binding
signal transducer activity
GTPase activator activity
receptor binding
protein binding
beta-catenin binding
protein C-terminus binding
enzyme binding
protein kinase binding
protein domain specific binding
receptor signaling complex scaffold activity
ubiquitin protein ligase binding
protein complex scaffold
identical protein binding
protein homodimerization activity
protein self-association
SMAD binding
armadillo repeat domain binding
I-SMAD binding
R-SMAD binding