MSS202416

• Gene Symbol: Bmpr2
• Gene Name: bone morphogenetic protein receptor, type II (serine/threonine kinase)
• Gene Aliases: 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, BMPRII, BRK-3, Gm20272
• Chromosome Location: Chr.1: 59764270 - 59878081 on Build GRCm38
• UniGene ID: Mm.391654
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bmpr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007561.4	NP_031587.1	12	2005
GenBank mRNA	AF003942.1	-	12	2005
	AK138715.1	-	2	133
	AK148180.1	-	7	823
	AK149385.1	-		2886
	U78048.1	-	12	1647

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_080407, XM_006244951, XM_006244952.

Gene Ontology Categories:

Process(es)

mesoderm formation
maternal placenta development
positive regulation of protein phosphorylation
endothelial cell proliferation
positive regulation of endothelial cell proliferation
lymphangiogenesis
blood vessel remodeling
chondrocyte development
negative regulation of systemic arterial blood pressure
transcription from RNA polymerase II promoter
protein phosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
anterior/posterior pattern specification
positive regulation of endothelial cell migration
positive regulation of epithelial cell migration
positive regulation of pathway-restricted SMAD protein phosphorylation
regulation of lung blood pressure
phosphorylation
negative regulation of cell growth
positive regulation of bone mineralization
BMP signaling pathway
positive regulation of BMP signaling pathway
regulation of cell proliferation
positive regulation of osteoblast differentiation
negative regulation of vasoconstriction
vascular endothelial growth factor receptor signaling pathway
lung alveolus development
positive regulation of axon extension involved in axon guidance
limb development
lymphatic endothelial cell differentiation
artery development
venous blood vessel development
retina vasculature development in camera-type eye
endothelial cell apoptotic process
negative regulation of chondrocyte proliferation
negative regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding
BMP binding
metal ion binding