MSS202675

• Gene Symbol: Runx2
• Gene Name: runt related transcription factor 2
• Gene Aliases: AML3, Cbf, Cbfa-1, Cbfa1, LS3, Osf2, PEBP2aA, Pebp2a1, Pebpa2a
• Chromosome Location: Chr.17: 44495986 - 44814831 on Build GRCm38
• UniGene ID: Mm.391013
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Runx2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145920.2	NP_001139392.1	2	1507
	NM_001146038.2	NP_001139510.1	4	772
	NM_001271627.1	NP_001258556.1	3	936
	NM_001271630.1	NP_001258559.1	2	1035
	NM_001271631.1	NP_001258560.1	2	1035
	NM_009820.5	NP_033950.2	4	739
GenBank mRNA	AF005936.1	-	3	890
	AF010284.1	-	4	739
	AF053954.1	-	3	353
	AF053955.1	-	2	187
	AF053956.1	-	2	225
	AK134925.1	-	2	293
	AK137061.1	-	1	118
	AK158925.1	-	2	1035
	D14636.1	-	2	1505
	D14637.1	-	2	1505
	DQ458792.1	-	3	524

More Information

Gene Ontology Categories:

Process(es)

skeletal system development
osteoblast differentiation
endochondral ossification
osteoblast fate commitment
chondrocyte differentiation
chondrocyte development
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
hemopoiesis
neuron differentiation
T cell differentiation
regulation of ossification
BMP signaling pathway
positive regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
regulation of fibroblast growth factor receptor signaling pathway
odontogenesis of dentin-containing tooth
regulation of odontogenesis of dentin-containing tooth
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
stem cell differentiation
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
ATP binding
transcription factor binding
protein domain specific binding
histone deacetylase binding
bHLH transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding