MSS209187

• Gene Symbol: Slit2
• Gene Name: slit homolog 2 (Drosophila)
• Gene Aliases: Drad-1, E030015M03Rik, E130320P19Rik, Slil3, mKIAA4141, slit-2
• Chromosome Location: Chr.5: 47983108 - 48306282 on Build GRCm38
• UniGene ID: Mm.289739
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Slit2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291227.1	NP_001278156.1	26	4519
	NM_001291228.1	NP_001278157.1	25	4495
	NM_178804.4	NP_848919.3	25	4483
GenBank mRNA	AF074960.1	-	11	1110
	AF144628.1	-	25	2844
	AK034918.1	-	1	1196
	AK053145.1	-	9	1313
	AK144573.1	-	25	4441
	AK220505.1	-	25	3079
	BC059267.1	-	9	872
	BC079911.1	-	25	2608
	BC145487.1	-	26	2863	9054050
	BC145488.1	-	25	2839	9054051
	BC150779.1	-	26	2863	9087690

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004787, BC117190, AB017168, AF133270, BC143978, and others.
This siRNA also targets the following transcripts in Rat: NM_022632, XM_008770210.

Gene Ontology Categories:

Process(es)

metanephros development
ureteric bud development
in utero embryonic development
negative regulation of protein phosphorylation
cell migration involved in sprouting angiogenesis
negative regulation of leukocyte chemotaxis
chemotaxis
multicellular organism development
nervous system development
axonogenesis
axon guidance
motor neuron axon guidance
negative regulation of cell proliferation
negative regulation of lamellipodium assembly
negative regulation of endothelial cell migration
negative regulation of gene expression
negative regulation of smooth muscle cell migration
single organismal cell-cell adhesion
olfactory bulb development
chemorepulsion involved in postnatal olfactory bulb interneuron migration
corticospinal neuron axon guidance through spinal cord
telencephalon cell migration
cell differentiation
negative regulation of cell growth
negative regulation of cell migration
negative regulation of axon extension
negative regulation of actin filament polymerization
retinal ganglion cell axon guidance
dorsal/ventral axon guidance
negative regulation of GTPase activity
Roundabout signaling pathway
positive regulation of apoptotic process
negative regulation of vascular permeability
branching morphogenesis of an epithelial tube
neuron projection morphogenesis
axon extension involved in axon guidance
negative regulation of inflammatory response
negative chemotaxis
induction of negative chemotaxis
negative regulation of small GTPase mediated signal transduction
mammary gland duct morphogenesis
mammary duct terminal end bud growth
negative regulation of chemokine-mediated signaling pathway
cellular response to heparin
negative regulation of smooth muscle cell chemotaxis
negative regulation of mononuclear cell migration
negative regulation of neutrophil chemotaxis
negative regulation of monocyte chemotaxis
negative regulation of retinal ganglion cell axon guidance
negative regulation of cellular response to growth factor stimulus

Function(s)

GTPase inhibitor activity
receptor binding
calcium ion binding
protein binding
heparin binding
identical protein binding
protein homodimerization activity
laminin-1 binding
proteoglycan binding
heparan sulfate proteoglycan binding
chemorepellent activity
Roundabout binding