MSS215272

• Gene Symbol: Nox1
• Gene Name: NADPH oxidase 1
• Gene Aliases: GP91-2, MOX1, NOH-1, NOH1, NOX1a, NOX1alpha, Nox-1
• Chromosome Location: Chr.X: 134086012 - 134137711 on Build GRCm38
• UniGene ID: Mm.233865
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nox1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_172203.2	NP_757340.1	11, 12	1589
GenBank mRNA	AF539799.1	-	11, 12	1443
	AK136432.1	-	11, 12	1504
	AY174116.1	-	8, 9	1184

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053683, AF152963.

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
angiogenesis
regulation of systemic arterial blood pressure by renin-angiotensin
superoxide metabolic process
transport
signal transduction
positive regulation of cell proliferation
proton transport
cell migration
extracellular matrix organization
regulation of ion transmembrane transport
superoxide anion generation
hydrogen peroxide metabolic process
positive regulation of MAPK cascade
positive regulation of integrin biosynthetic process
positive regulation of JNK cascade
positive regulation of smooth muscle cell proliferation
intracellular pH elevation
oxidation-reduction process
cellular response to hyperoxia
oxygen metabolic process
cation transmembrane transport
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
cellular stress response to acidic pH
positive regulation of reactive oxygen species metabolic process

Function(s)

N-ethylmaleimide reductase activity
superoxide-generating NADPH oxidase activity
oxidoreductase activity
voltage-gated proton channel activity
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
metal ion binding
Rac GTPase binding
epoxyqueuosine reductase activity