MSS218456

• Gene Symbol: Axl
• Gene Name: AXL receptor tyrosine kinase
• Gene Aliases: AI323647, Ark, Tyro7, Ufo
• Chromosome Location: Chr.7: 25756500 - 25788733 on Build GRCm38
• UniGene ID: Mm.4128
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Axl
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001190974.1	NP_001177903.1	14	1941
	NM_001190975.1	NP_001177904.1	13	1677
	NM_009465.4	NP_033491.2	15	1968
GenBank mRNA	AK033237.1	-	14	1910
	AK155567.1	-	16	1854
	AK161294.1	-	8	641
	AK170010.1	-	14	1915
	AK170897.1	-	14	1575
	AK200128.1	-	3	148
	BC008551.1	-	10	1058
	BC046618.1	-	15	1805	6494383
	BC050914.1	-	15	1776	6418252
	BC058230.1	-	15	1829	6313662
	X63535.1	-	15	1717

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001013147, NM_031794.

Gene Ontology Categories:

Process(es)

neuron migration
natural killer cell differentiation
positive regulation of cytokine-mediated signaling pathway
blood vessel remodeling
immune system process
protein phosphorylation
phagocytosis
inflammatory response
enzyme linked receptor protein signaling pathway
spermatogenesis
phosphorylation
peptidyl-tyrosine phosphorylation
forebrain cell migration
cell differentiation
platelet activation
cellular response to extracellular stimulus
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
secretion by cell
erythrocyte homeostasis
substrate adhesion-dependent cell spreading
cellular response to interferon-alpha
ovulation cycle
negative regulation of apoptotic process
apoptotic cell clearance
protein kinase B signaling
negative regulation of neuron apoptotic process
innate immune response
viral entry into host cell
positive regulation of pinocytosis
negative regulation of lymphocyte activation
positive regulation of protein kinase B signaling
vagina development
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
negative regulation of dendritic cell apoptotic process

Function(s)

nucleotide binding
phosphatidylserine binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
myosin heavy chain binding
phosphatidylinositol 3-kinase binding
protein heterodimerization activity