MSS219221

• Gene Symbol: Klrk1
• Gene Name: killer cell lectin-like receptor subfamily K, member 1
• Gene Aliases: D6H12S2489E, NKG2-D, Nkg2d
• Chromosome Location: Chr.6: 129610323 - 129623864 on Build GRCm38
• UniGene ID: Mm.8217
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Klrk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001083322.2	NP_001076791.1	2	96
	NM_001286018.1	NP_001272947.1	2	96
	NM_033078.4	NP_149069.1	2	189
GenBank mRNA	AA174479.1	-	2	205
	AF030313.1	-	2	73
	AF039026.1	-	2	103
	AF054819.1	-	3	363
	AK040436.1	-	2	178
	AK170499.1	-	2	97
	AY860972.1	-	2	79
	BC057147.1	-	2	140	5328432
	CT010384.1	-	2	79

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133512, XM_006237074, XM_006237076, XM_006237077, XM_006237073, and others.

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
immune system process
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
natural killer cell activation
cell differentiation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of apoptotic process
innate immune response
positive regulation of nitric oxide biosynthetic process
positive regulation of natural killer cell mediated cytotoxicity
defense response to Gram-positive bacterium
cellular response to lipopolysaccharide

Function(s)

protein binding
kinase binding
carbohydrate binding
MHC class Ib receptor activity
MHC class I protein binding
protein homodimerization activity