MSS222826

• Gene Symbol: Irs2
• Gene Name: insulin receptor substrate 2
• Gene Aliases: Irs-2
• Chromosome Location: Chr.8: 10986961 - 11008430 on Build GRCm38
• UniGene ID: Mm.407207
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Irs2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001081212.1	NP_001074681.1	1	3713
GenBank mRNA	AK155277.1	-	1	3535
	BC147580.1	-	1	3741	9056570

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001168633.

Gene Ontology Categories:

Process(es)

positive regulation of mesenchymal cell proliferation
negative regulation of B cell apoptotic process
signal transduction
brain development
cell proliferation
positive regulation of cell proliferation
insulin receptor signaling pathway
response to glucose
negative regulation of plasma membrane long-chain fatty acid transport
positive regulation of glucose metabolic process
regulation of lipid metabolic process
positive regulation of cell migration
mammary gland development
positive regulation of B cell proliferation
positive regulation of fatty acid beta-oxidation
positive regulation of insulin secretion
cellular response to insulin stimulus
negative regulation of kinase activity
positive regulation of glycogen biosynthetic process
positive regulation of glucose import

Function(s)

signal transducer activity
insulin receptor binding
protein binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
phosphatidylinositol 3-kinase binding
14-3-3 protein binding