MSS236034

• Gene Symbol: Bcl2l1
• Gene Name: BCL2-like 1
• Gene Aliases: Bcl(X)L, Bcl-XL, Bcl2l, BclX, bcl-x, bcl2-L-1
• Chromosome Location: Chr.2: 152758732 - 152832581 on Build GRCm38
• UniGene ID: Mm.238213
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bcl2l1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001289716.1	NP_001276645.1	2	900
	NM_001289717.1	NP_001276646.1	2	745
	NM_001289739.1	NP_001276668.1	2	900
	NM_009743.5	NP_033873.3	2	694
GenBank mRNA	AK146461.1	-	2	850
	AK150028.1	-	2	637
	AK172250.1	-	2	661
	BC089016.1	-	2	648	30606568
	BC089017.1	-	1	485	30605282
	L35049.1	-	2	698
	U10101.1	-	1	456
	U10102.1	-	2	693
	U51277.1	-	2	833
	U51278.1	-	1	558
	U51279.1	-	2	691
	X83574.1	-	1	456

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_138578, Z23115, CR936637, BT007208, BC019307, and others.
This siRNA also targets the following transcripts in Rat: NM_001033672, NM_001033670, NM_031535, XM_006235264, XM_006235265, and others.

Gene Ontology Categories:

Process(es)

cytokinesis
ovarian follicle development
in utero embryonic development
release of cytochrome c from mitochondria
response to ischemia
apoptotic process
mitotic cell cycle checkpoint
germ cell development
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to radiation
fertilization
response to virus
suppression by virus of host apoptotic process
response to cytokine
growth
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
response to cycloheximide
regulation of mitochondrial membrane permeability
neuron apoptotic process
regulation of mitochondrial membrane potential
cellular process regulating host cell cycle in response to virus
mitochondrion morphogenesis
cellular response to amino acid stimulus
cellular response to alkaloid
cellular response to gamma radiation
apoptotic process in bone marrow
negative regulation of establishment of protein localization to plasma membrane
negative regulation of release of cytochrome c from mitochondria
extrinsic apoptotic signaling pathway in absence of ligand
hepatocyte apoptotic process
negative regulation of execution phase of apoptosis
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of anoikis
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein kinase binding
identical protein binding
protein homodimerization activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
protein heterodimerization activity
BH domain binding
BH3 domain binding
MDM2/MDM4 family protein binding