MSS273952

• Gene Symbol: Ddit3
• Gene Name: DNA-damage inducible transcript 3
• Gene Aliases: CHOP-10, CHOP10, chop, gadd153
• Chromosome Location: Chr.10: 127290793 - 127296288 on Build GRCm38
• UniGene ID: Mm.110220
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ddit3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290183.1	NP_001277112.1	3	364
	NM_007837.4	NP_031863.3	4	412
GenBank mRNA	AK028120.1	-	4	409
	BC013718.1	-	4	407	4012433
	BE134148.1	-	1	464
	CF982562.1	-	1	62
	X67083.1	-	3	319

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109986, NM_024134, XM_006241445, XM_006241444, BF282473, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
ER overload response
response to unfolded protein
cell cycle
cell cycle arrest
Wnt signaling pathway
endoplasmic reticulum unfolded protein response
positive regulation of interleukin-8 production
negative regulation of CREB transcription factor activity
response to endoplasmic reticulum stress
response to starvation
mRNA transcription from RNA polymerase II promoter
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
regulation of transcription involved in anterior/posterior axis specification
cell redox homeostasis
negative regulation of fat cell differentiation
negative regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
release of sequestered calcium ion into cytosol
negative regulation of protein kinase B signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
negative regulation of canonical Wnt signaling pathway
positive regulation of neuron death
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
negative regulation of determination of dorsal identity

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
cAMP response element binding protein binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity