MSS275055

• Gene Symbol: Ikbkb
• Gene Name: inhibitor of kappaB kinase beta
• Gene Aliases: AI132552, IKK-2, IKK-beta, IKK2, IKK[b], IKKbeta
• Chromosome Location: Chr.8: 22659205 - 22706585 on Build GRCm38
• UniGene ID: Mm.277886
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ikbkb
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001159774.1	NP_001153246.1	11, 12	1247
	NM_010546.2	NP_034676.1	11, 12	1247
GenBank mRNA	AF026524.1	-	10, 11	1115
	AF088910.1	-	11, 12	1307
	AK086442.1	-	9, 10	1064
	AK144603.1	-	11, 12	1240
	AK150884.1	-	11, 12	1199
	AK151888.1	-	11, 12	1199
	AK151955.1	-	11, 12	1199
	AK153151.1	-	11, 12	1199
	AK155587.1	-	11, 12	1180
	AK156294.1	-	11, 12	1205
	BC004772.1	-	11, 12	1185
	BC037723.1	-	11, 12	1219	4482634

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053355, AF115282.

Gene Ontology Categories:

Process(es)

B cell homeostasis
protein phosphorylation
I-kappaB phosphorylation
positive regulation of cell proliferation
positive regulation of sodium ion transport
phosphorylation
signal transduction by protein phosphorylation
neuron projection development
serine phosphorylation of STAT protein
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NF-kappaB transcription factor activity
cellular response to tumor necrosis factor
positive regulation of neuron death
positive regulation of cation channel activity

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding