MSS278551

• Gene Symbol: Tsc2
• Gene Name: tuberous sclerosis 2
• Gene Aliases: Nafld, Tcs2
• Chromosome Location: Chr.17: 24595816 - 24632627 on Build GRCm38
• UniGene ID: Mm.30435
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tsc2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039363.2	NP_001034452.1	12, 13	1378
	NM_001286713.1	NP_001273642.1	12, 13	1378
	NM_001286714.1	NP_001273643.1	12, 13	1373
	NM_001286716.1	NP_001273645.1	12, 13	1373
	NM_001286718.1	NP_001273647.1	12, 13	1378
	NM_001286720.1	NP_001273649.1	12, 13	1378
	NM_011647.3	NP_035777.2	12, 13	1378
GenBank mRNA	AF132986.1	-	8, 9	906
	AK143799.1	-	12, 13	1379
	AK147016.1	-	12, 13	1354
	AK147302.1	-	12, 13	1318
	AK147487.1	-	12, 13	1347
	AK147874.1	-	12, 13	1343
	AK147908.1	-	12, 13	1379
	AK148062.1	-	12, 13	1370
	AK148072.1	-	12, 13	1275
	AK170589.1	-	12, 13	1369
	AK171007.1	-	12, 13	1347
	AK217801.1	-	1, 2	127
	AK218975.1	-	1, 2	127
	BC052449.1	-	12, 13	1354	6409037
	BC060701.1	-	12, 13	1354	6409037
	U37775.1	-	11, 12	1290
	U39818.1	-	12, 13	1349

More Information

Gene Ontology Categories:

Process(es)

response to hypoxia
neural tube closure
negative regulation of protein kinase activity
protein import into nucleus
signal transduction
heart development
protein localization
negative regulation of cell proliferation
phosphatidylinositol 3-kinase signaling
negative regulation of phosphatidylinositol 3-kinase signaling
cell projection organization
regulation of endocytosis
negative regulation of Wnt signaling pathway
negative regulation of TOR signaling
cellular response to insulin stimulus
negative regulation of MAP kinase activity
protein kinase B signaling
positive regulation of GTPase activity
protein transport into plasma membrane raft
establishment of protein localization
negative regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
glucose import
regulation of insulin receptor signaling pathway
negative regulation of insulin receptor signaling pathway
insulin-like growth factor receptor signaling pathway
negative regulation of epithelial cell proliferation
positive chemotaxis
regulation of small GTPase mediated signal transduction
protein homooligomerization
protein heterooligomerization
regulation of cell cycle
negative regulation of protein kinase B signaling

Function(s)

GTPase activator activity
protein binding
phosphatase binding
protein homodimerization activity
protein heterodimerization activity
14-3-3 protein binding