MSS290454

• Gene Symbol: Pink1
• Gene Name: PTEN induced putative kinase 1
• Gene Aliases: 1190006F07Rik, AU042772, AW557854, BRPK, mFLJ00387
• Chromosome Location: Chr.4: 138313409 - 138326296 on Build GRCm38
• UniGene ID: Mm.18539
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pink1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_026880.2	NP_081156.2	2	728
GenBank mRNA	AB053476.1	-	2	660
	AF316872.1	-	2	706
	AK050322.1	-	2	708
	AK155474.1	-	2	714
	AK165480.1	-	2	707
	AK188455.1	-	1	256
	AK213702.1	-	1	69
	AK220318.1	-	2	682
	BC018561.1	-	2	554
	BC018594.1	-	2	691
	BC067066.1	-	2	696	30542123
	BC069968.1	-	3	586

More Information

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
regulation of oxidative phosphorylation
protein phosphorylation
autophagy
response to stress
response to oxidative stress
mitochondrion organization
regulation of hydrogen peroxide metabolic process
negative regulation of gene expression
regulation of mitochondrion organization
positive regulation of macroautophagy
negative regulation of macroautophagy
phosphorylation
protein ubiquitination
peptidyl-serine phosphorylation
respiratory electron transport chain
regulation of protein ubiquitination
positive regulation of synaptic transmission, dopaminergic
positive regulation of peptidyl-serine phosphorylation
positive regulation of dopamine secretion
positive regulation of catecholamine secretion
cellular response to oxidative stress
positive regulation of protein dephosphorylation
intracellular signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of protein complex assembly
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
positive regulation of translation
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of mitochondrial membrane potential
cellular response to hypoxia
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
negative regulation of mitochondrial fission
cellular response to toxic substance
mitophagy in response to mitochondrial depolarization
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of autophagosome assembly
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of mitophagy
negative regulation of oxidative stress-induced cell death
regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of cristae formation
positive regulation of protein targeting to mitochondrion
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

nucleotide binding
magnesium ion binding
protease binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
calcium-dependent protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ubiquitin protein ligase binding
protein kinase B binding
metal ion binding
C3HC4-type RING finger domain binding