RSS302664

• Gene Symbol: Ptpn1
• Gene Name: protein tyrosine phosphatase, non-receptor type 1
• Gene Aliases: Ptp
• Chromosome Location: Chr.3: 164665462 - 164714641 on Build Rnor_6.0
• UniGene ID: Rn.11317
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptpn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012637.2	NP_036769.1	4, 5	420
	XM_006235638.2	XP_006235700.1	4, 5	489
	XM_006235639.2	XP_006235701.1	4, 5	490
GenBank mRNA	BC081829.1	-	4, 5	420	7135855
	M33962.1	-	4, 5	462

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011201, AK166020, AK150322, AK165949, AK153088, and others.

Gene Ontology Categories:

Process(es)

protein dephosphorylation
insulin receptor signaling pathway
regulation of signal transduction
regulation of endocytosis
negative regulation of vascular endothelial growth factor receptor signaling pathway
endoplasmic reticulum unfolded protein response
actin cytoskeleton reorganization
peptidyl-tyrosine dephosphorylation
platelet-derived growth factor receptor-beta signaling pathway
regulation of insulin receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

Function(s)

protein tyrosine phosphatase activity
insulin receptor binding
protein binding
zinc ion binding
enzyme binding
protein kinase binding
receptor tyrosine kinase binding
poly(A) RNA binding
ephrin receptor binding
protein phosphatase 2A binding