RSS302990

• Gene Symbol: Ntrk2
• Gene Name: neurotrophic tyrosine kinase, receptor, type 2
• Gene Aliases: RATTRKB1, TRKB1, Tkrb, trk-B, trkB
• Chromosome Location: Chr.17: 5934690 - 6245662 on Build Rnor_6.0
• UniGene ID: Rn.11246
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ntrk2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001163168.2	NP_001156640.1	8	1413
	NM_012731.2	NP_036863.1	8	1398
	XM_006253507.2	XP_006253569.1	8	1349
	XM_008771425.1	XP_008769647.1	8	1354
	XM_008771426.1	XP_008769648.1	8	1240
	XM_008771427.1	XP_008769649.1	8	1348
GenBank mRNA	AY265419.1	-	8	1178
	KC855568.1	-	2	102
	M55291.1	-	8	1401
	M55292.1	-	8	1178
	M55293.1	-	7	845

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001018066, NM_001007097, NM_001018064, NM_001018065, NM_006180, and others.
This siRNA also targets the following transcripts in Mouse: NM_001282961, NM_008745, NM_001025074, AK147441, M33385, and others.

Gene Ontology Categories:

Process(es)

vasculogenesis
neuron migration
inflammatory response
neuromuscular junction development
aging
learning
long-term memory
circadian rhythm
feeding behavior
positive regulation of cell proliferation
response to light stimulus
positive regulation of gene expression
positive regulation of neuron projection development
response to auditory stimulus
glutamate secretion
positive regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
regulation of metabolic process
central nervous system neuron development
cerebral cortex development
neuron differentiation
brain-derived neurotrophic factor receptor signaling pathway
positive regulation of peptidyl-serine phosphorylation
calcium-mediated signaling using intracellular calcium source
neurotrophin signaling pathway
mechanoreceptor differentiation
regulation of MAPK cascade
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
retinal rod cell development
protein autophosphorylation
regulation of neurotransmitter secretion
oligodendrocyte differentiation
peripheral nervous system neuron development
positive regulation of axonogenesis
regulation of dendrite development
regulation of protein kinase B signaling
positive regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
cellular response to tumor necrosis factor
cellular response to nerve growth factor stimulus
cellular response to brain-derived neurotrophic factor stimulus
positive regulation of glucocorticoid receptor signaling pathway
negative regulation of anoikis

Function(s)

transmembrane receptor protein tyrosine kinase activity
neurotrophin receptor activity
protein binding
ATP binding
protein homodimerization activity
neurotrophin binding
ephrin receptor binding
brain-derived neurotrophic factor binding
brain-derived neurotrophic factor-activated receptor activity