RSS309825

• Gene Symbol: Ptgs2
• Gene Name: prostaglandin-endoperoxide synthase 2
• Gene Aliases: COX-2, Cox2
• Chromosome Location: Chr.13: 67351230 - 67356920 on Build Rnor_6.0
• UniGene ID: Rn.217585
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptgs2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017232.3	NP_058928.3	10	1758
GenBank mRNA	AF233596.1	-		1882
	L20085.1	-	10	1758
	L25925.1	-	10	1764
	S67722.1	-		1882
	U03389.1	-		1882
	U04300.1	-	10	1758

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011198, AK049923, AK166221, AK172161, M64291, and others.

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
angiogenesis
inflammatory response
response to oxidative stress
embryo implantation
learning
memory
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
response to radiation
response to fructose
response to organic substance
response to manganese ion
response to lithium ion
response to organonitrogen compound
positive regulation of vascular endothelial growth factor production
positive regulation of cell death
response to organic cyclic compound
sensory perception of pain
cyclooxygenase pathway
bone mineralization
ovulation
positive regulation of fever generation
positive regulation of synaptic plasticity
negative regulation of synaptic transmission, dopaminergic
response to estradiol
response to lipopolysaccharide
response to vitamin D
response to cytokine
response to tumor necrosis factor
cellular response to UV
maintenance of blood-brain barrier
regulation of cell proliferation
positive regulation of NF-kappaB import into nucleus
response to drug
hair cycle
positive regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
negative regulation of cell cycle
positive regulation of vasoconstriction
negative regulation of smooth muscle contraction
positive regulation of smooth muscle contraction
decidualization
positive regulation of smooth muscle cell proliferation
brown fat cell differentiation
response to glucocorticoid
negative regulation of calcium ion transport
positive regulation of synaptic transmission, glutamatergic
oxidation-reduction process
response to fatty acid
cellular response to mechanical stimulus
cellular response to ATP
cellular response to hypoxia
cellular response to fluid shear stress
positive regulation of transforming growth factor beta production
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of fibroblast growth factor production
positive regulation of brown fat cell differentiation
positive regulation of platelet-derived growth factor production

Function(s)

peroxidase activity
prostaglandin-endoperoxide synthase activity
protein binding
lipid binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
enzyme binding
heme binding
protein homodimerization activity
metal ion binding