RSS321069

• Gene Symbol: Irak3
• Gene Name: interleukin-1 receptor-associated kinase 3
• Gene Aliases: -
• Chromosome Location: Chr.7: 64923751 - 64982224 on Build Rnor_6.0
• UniGene ID: Rn.147737
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Irak3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001108101.1	NP_001101571.1	7	857
GenBank mRNA	BC166731.1	-	7	932	7934689

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_028679, AF461763, AK014783, BC120829, AJ440757, and others.

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
protein phosphorylation
biological_process
positive regulation of macrophage tolerance induction
negative regulation of macrophage cytokine production
cytokine-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
response to peptidoglycan
response to lipopolysaccharide
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
negative regulation of protein catabolic process
negative regulation of protein complex disassembly
regulation of protein complex disassembly
response to exogenous dsRNA
negative regulation of MAP kinase activity
negative regulation of innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
interleukin-1-mediated signaling pathway
response to interleukin-1

Function(s)

magnesium ion binding
molecular_function
protein kinase activity
protein serine/threonine kinase activity
ATP binding
protein homodimerization activity
protein heterodimerization activity