RSS355371

• Gene Symbol: Map2k5
• Gene Name: mitogen activated protein kinase kinase 5
• Gene Aliases: Mek5
• Chromosome Location: Chr.8: 68055976 - 68282641 on Build Rnor_6.0
• UniGene ID: Rn.11054
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map2k5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033987.1	NP_001029159.1	10	1233
	NM_017246.2	NP_058942.1	10	1233
	XM_006243229.2	XP_006243291.1	10	1292
	XM_008766221.1	XP_008764443.1	8	431
GenBank mRNA	BC078860.1	-	10	1233	7122708
	U37462.1	-	10	721
	U37463.1	-	8	442
	U37464.1	-	10	721

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
protein phosphorylation
heart development
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
negative regulation of heterotypic cell-cell adhesion
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of protein metabolic process
negative regulation of response to cytokine stimulus
ERK5 cascade
cellular response to growth factor stimulus
negative regulation of cell migration involved in sprouting angiogenesis
negative regulation of chemokine (C-X-C motif) ligand 2 production
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
ATP binding
metal ion binding