RSS356199

• Gene Symbol: Pink1
• Gene Name: PTEN induced putative kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.5: 156677146 - 156689258 on Build Rnor_6.0
• UniGene ID: Rn.219286
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pink1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001106694.1	NP_001100164.1	1, 2	414
GenBank mRNA	BC169047.1	-	1, 2	408	7190543

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_032409, AB053323, AF316873, BC028215.
This siRNA also targets the following transcripts in Mouse: NM_026880, AK050322, BC067066, AF316872, AB053476, and others.

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
protein phosphorylation
response to oxidative stress
mitochondrion organization
biological_process
regulation of hydrogen peroxide metabolic process
negative regulation of gene expression
negative regulation of macroautophagy
protein ubiquitination
peptidyl-serine phosphorylation
respiratory electron transport chain
regulation of protein ubiquitination
positive regulation of synaptic transmission, dopaminergic
positive regulation of peptidyl-serine phosphorylation
positive regulation of dopamine secretion
positive regulation of catecholamine secretion
cellular response to oxidative stress
positive regulation of protein dephosphorylation
intracellular signal transduction
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of protein complex assembly
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
positive regulation of translation
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of mitochondrial membrane potential
cellular response to hypoxia
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
negative regulation of mitochondrial fission
cellular response to toxic substance
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of autophagosome assembly
negative regulation of mitophagy
negative regulation of oxidative stress-induced cell death
regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of cristae formation
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

magnesium ion binding
protease binding
molecular_function
protein serine/threonine kinase activity
protein binding
ATP binding
calcium-dependent protein kinase activity
kinase activity
ubiquitin protein ligase binding
protein kinase B binding
C3HC4-type RING finger domain binding