n309239

• Gene Symbol: MITF
• Gene Name: melanogenesis associated transcription factor
• Gene Aliases: CMM8, MI, WS2, WS2A, bHLHe32
• Chromosome Location: Chr.3: 69739435 - 69968337 on Build GRCh38
• UniGene ID: Hs.166017
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MITF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_198177.2	NP_937820.1	1	52
	XM_005264755.3	XP_005264812.1	1	194
	XM_011533723.2	XP_011532025.1	1	196
GenBank mRNA	AB006989.1	-	1	42
	DC388606.1	-	1	52

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	DC422081.1	-	1	52		Chr. 3 - 69866224 - 69937980 [+] on Build GRCh38
GenBankmRNA	DC392461.1	-	1	52		Chr. 3 - 69866224 - 69938028 [+] on Build GRCh38
GenBankmRNA	BP277367.1	-	1	54		Chr. 3 - 69866225 - 69938013 [+] on Build GRCh38
GenBankmRNA	DC362311.1	-	1	34		Chr. 3 - 69866242 - 69938042 [+] on Build GRCh38
GenBankmRNA	DC361712.1	-	1	52		Chr. 3 - 69866224 - 69938033 [+] on Build GRCh38
GenBankmRNA	DC354465.1	-	1	52		Chr. 3 - 69866224 - 69938035 [+] on Build GRCh38
GenBankmRNA	CN481686.1	-	1	19		Chr. 3 - 69866257 - 69939153 [+] on Build GRCh38
GenBankmRNA	DC362467.1	-	1	40		Chr. 3 - 69866236 - 69938034 [+] on Build GRCh38
GenBankmRNA	HY163756.1	-	1	23		Chr. 3 - 69866253 - 69938011 [+] on Build GRCh38
GenBankmRNA	DC362352.1	-	1	52		Chr. 3 - 69866224 - 69938009 [+] on Build GRCh38
GenBankmRNA	BP276751.1	-	1	51		Chr. 3 - 69866224 - 69938030 [+] on Build GRCh38

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AK052895.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
multicellular organism development
positive regulation of gene expression
protein sumoylation
melanocyte differentiation
regulation of apoptotic process
regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mast cell migration
positive regulation of DNA-templated transcription, initiation
regulation of RNA biosynthetic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
protein dimerization activity