n336106

• Gene Symbol: IKBKB
• Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• Gene Aliases: IKK-beta, IKK2, IKKB, IMD15, NFKBIKB
• Chromosome Location: Chr.8: 42271302 - 42332653 on Build GRCh38
• UniGene ID: Hs.597664
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IKBKB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_005273490.2	XP_005273547.1	21	3312
	XM_005273491.4	XP_005273548.1	20	3212
	XM_005273493.3	XP_005273550.1	18	3008
	XM_005273495.2	XP_005273552.1	20	3053
	XM_005273496.3	XP_005273553.1	19	3073
	XM_005273498.3	XP_005273555.1	17	2882
	XM_011544517.2	XP_011542819.1	21	3310
	XM_011544518.2	XP_011542820.1	20	3162
	XM_011544519.2	XP_011542821.1	20	3180
	XM_011544520.2	XP_011542822.1	18	3027
	XM_011544521.2	XP_011542823.1	19	3140
	XM_011544522.2	XP_011542824.1	18	2988
	XM_017013396.1	XP_016868885.1	20	3265
GenBank mRNA	AK093537.1	-	1	100
	AK095687.1	-	1	798

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	DB109959.1	-	1	433		Chr. 8 - 42329703 - 42330278 [+] on Build GRCh38
GenBankmRNA	DA953030.1	-	1	217		Chr. 8 - 42329921 - 42330500 [+] on Build GRCh38

More Information

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
skeletal muscle contraction
protein phosphorylation
inflammatory response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
positive regulation of cell proliferation
response to virus
response to toxic substance
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
cortical actin cytoskeleton organization
neuron projection development
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
negative regulation of myosin-light-chain-phosphatase activity
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
regulation of phosphorylation
response to drug
serine phosphorylation of STAT protein
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
nucleotide-binding oligomerization domain containing signaling pathway
interleukin-1-mediated signaling pathway
response to fatty acid
cellular response to tumor necrosis factor
establishment of protein localization to plasma membrane
positive regulation of neuron death
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding