s101262

• Gene Symbol: Flna
• Gene Name: filamin, alpha
• Gene Aliases: ABP-280, Dilp2, F730004A14Rik, Fln1, GENA 379, filamin-1
• Chromosome Location: Chr.X: 74223461 - 74249854 on Build GRCm38
• UniGene ID: Mm.295533
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Flna
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290421.1	NP_001277350.1	45	7486
	NM_010227.3	NP_034357.2	44	7464
GenBank mRNA	AK131179.1	-	32	5305
	BC004061.1	-	7	985
	BC038478.1	-	45	7361
	BC039208.1	-	24	3676
	BC054432.1	-	1	64
	BC099506.1	-	2	236
	BC151024.1	-	44	7455	9087937

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134599, XM_006229569, XM_006229570, FQ227568, FQ232712, and others.

Gene Ontology Categories:

Process(es)

epithelial to mesenchymal transition
adenylate cyclase-inhibiting dopamine receptor signaling pathway
negative regulation of transcription from RNA polymerase I promoter
cell projection organization
actin cytoskeleton organization
actin cytoskeleton reorganization
protein localization to cell surface
negative regulation of protein catabolic process
cilium assembly
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
receptor clustering
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of sequence-specific DNA binding transcription factor activity
early endosome to late endosome transport
establishment of protein localization
protein stabilization
cytoplasmic sequestering of protein
actin crosslink formation
platelet aggregation
mitotic spindle assembly
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of integrin-mediated signaling pathway

Function(s)

glycoprotein binding
actin binding
signal transducer activity
protein kinase C binding
protein binding
transcription factor binding
Rho GTPase binding
Ral GTPase binding
small GTPase binding
mu-type opioid receptor binding
protein complex binding
Fc-gamma receptor I complex binding
protein homodimerization activity
poly(A) RNA binding
SMAD binding
Rac GTPase binding
actin filament binding