s10524 Validated

• Gene Symbol: PIK3CB
• Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
• Gene Aliases: P110BETA, PI3K, PI3KBETA, PIK3C1
• Chromosome Location: Chr.3: 138652698 - 138834938 on Build GRCh38
• UniGene ID: Hs.239818
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PIK3CB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256045.1	NP_001242974.1	8	1339
	NM_006219.2	NP_006210.1	17	2473
	XM_005247530.2	XP_005247587.1	19	2822
	XM_006713659.3	XP_006713722.1	18	2693
	XM_011512895.2	XP_011511197.1	20	2818
	XM_011512896.1	XP_011511198.1	15	2087
	XM_017006619.1	XP_016862108.1	18	2496
	XM_017006620.1	XP_016862109.1	17	2243
	XM_017006621.1	XP_016862110.1	16	2192
GenBank mRNA	AK293754.1	-	8	1339
	AK302937.1	-	10	1352
	BC003393.1	-	2	106
	BC114432.1	-	17	2461	40008544
	CR749357.1	-	10	1058
	S67334.1	-	17	2457

More Information

Matching Taqman Gene Expression Assay:

Hs00178872_m1

Gene Ontology Categories:

Process(es)

activation of MAPK activity
endothelial cell proliferation
regulation of cell-matrix adhesion
phosphatidylinositol biosynthetic process
cellular calcium ion homeostasis
autophagy
chemotaxis
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of autophagy
positive regulation of gene expression
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
cell migration
platelet activation
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
embryonic cleavage
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
angiogenesis involved in wound healing
platelet aggregation
regulation of clathrin-mediated endocytosis

Function(s)

protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity