s10545 Validated

• Gene Symbol: PIN1
• Gene Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
• Gene Aliases: DOD, UBL5
• Chromosome Location: Chr.19: 9835207 - 9849689 on Build GRCh38
• UniGene ID: Hs.465849
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PIN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006221.3	NP_006212.1	1, 2	204
	XM_011528068.2	XP_011526370.1	3, 4	195
GenBank mRNA	AF086512.1	-	1, 2	71
	AK092970.1	-	1	2216
	AK097558.1	-	1, 2	88
	AK291074.1	-	1, 2	88
	BC002899.1	-	1, 2	93	3941595
	BI827520.1	-	1, 2	209
	BI827672.1	-	1, 2	207
	BT019331.1	-	1, 2	66
	CR407654.1	-	1, 2	66
	U49070.1	-	1, 2	90

More Information

Matching Taqman Gene Expression Assay:

Hs00749260_s1

Gene Ontology Categories:

Process(es)

protein peptidyl-prolyl isomerization
positive regulation of protein phosphorylation
cell cycle
regulation of mitotic nuclear division
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
regulation of cytokinesis
negative regulation of type I interferon production
positive regulation of protein dephosphorylation
negative regulation of protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
synapse organization
protein stabilization
positive regulation of ubiquitin-protein transferase activity
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of cell growth involved in cardiac muscle cell development
negative regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway
regulation of protein localization to nucleus
regulation of signal transduction by p53 class mediator
negative regulation of cell motility

Function(s)

peptidyl-prolyl cis-trans isomerase activity
motor activity
protein binding
beta-catenin binding
mitogen-activated protein kinase kinase binding
GTPase activating protein binding
phosphoserine binding
phosphothreonine binding