s10631

• Gene Symbol: PLCG1
• Gene Name: phospholipase C gamma 1
• Gene Aliases: NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
• Chromosome Location: Chr.20: 41137519 - 41175721 on Build GRCh38
• UniGene ID: Hs.268177
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PLCG1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002660.2	NP_002651.2	24	2894
	NM_182811.1	NP_877963.1	24	2894
	XM_005260438.2	XP_005260495.1	24	2896
	XM_011528865.1	XP_011527167.1	24	2761
	XM_011528867.2	XP_011527169.1	24	2845
GenBank mRNA	AB210028.1	-	24	3178
	AK297370.1	-	13	1644
	AK309606.1	-	7	853
	AL110247.1	-	6	628
	BC136466.1	-	24	2861	9020455
	BC144136.1	-	24	2861	9052656
	M34667.1	-	24	2849

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013187, J03806.
This siRNA also targets the following transcripts in Mouse: NM_021280, X95346, BC065091, BC057161, AK134041, and others.

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
in utero embryonic development
signal transduction
epidermal growth factor receptor signaling pathway
phospholipid catabolic process
positive regulation of epithelial cell migration
viral process
cell migration
calcium-mediated signaling
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of blood vessel endothelial cell migration
inositol phosphate metabolic process
positive regulation of angiogenesis
T cell receptor signaling pathway
leukocyte migration
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus

Function(s)

phosphatidylinositol phospholipase C activity
phospholipase C activity
receptor signaling protein activity
neurotrophin TRKA receptor binding
calcium ion binding
protein binding
protein kinase binding
receptor tyrosine kinase binding
glutamate receptor binding