s109683

• Gene Symbol: Pde5a
• Gene Name: phosphodiesterase 5A, cGMP-specific
• Gene Aliases: Cgbpde, Cn5n, Pde5, Pde5a1
• Chromosome Location: Chr.3: 122729158 - 122859374 on Build GRCm38
• UniGene ID: Mm.134911
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde5a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_153422.2	NP_700471.2	12	1724
GenBank mRNA	AF541937.1	-	12	1724
	BC119137.1	-	12	1687	8733886
	BC120486.1	-	12	1687	40129409

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133584, XM_006233260, U76032, D89093.

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
positive regulation of chronic inflammatory response
signal transduction
short-term memory
metabolic process
positive regulation of cardiac muscle hypertrophy
regulation of cGMP metabolic process
negative regulation of T cell proliferation
positive regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of vasoconstriction
cGMP metabolic process
cGMP catabolic process
negative regulation of cardiac muscle contraction
relaxation of cardiac muscle
positive regulation of oocyte development

Function(s)

nucleotide binding
catalytic activity
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
phosphoric diester hydrolase activity
hydrolase activity
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity