s12627

• Gene Symbol: XCL1
• Gene Name: X-C motif chemokine ligand 1
• Gene Aliases: ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1
• Chromosome Location: Chr.1: 168574128 - 168582077 on Build GRCh38
• UniGene ID: Hs.546295
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: XCL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002995.2	NP_002986.1	3	952
GenBank mRNA	D43768.1	-	3	807

More Information

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
monocyte chemotaxis
positive regulation of leukocyte chemotaxis
negative regulation of T cell cytokine production
positive regulation of T cell cytokine production
negative regulation of T-helper 1 type immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
response to virus
positive regulation of T cell chemotaxis
neutrophil chemotaxis
negative regulation of interferon-gamma production
negative regulation of interleukin-2 production
positive regulation of interleukin-10 production
mature natural killer cell chemotaxis
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of transcription, DNA-templated
regulation of inflammatory response
positive regulation of inflammatory response
release of sequestered calcium ion into cytosol
positive regulation of release of sequestered calcium ion into cytosol
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to interleukin-4
cellular response to tumor necrosis factor
cellular response to transforming growth factor beta stimulus
positive regulation of transforming growth factor beta production
positive regulation of granzyme B production
positive regulation of neutrophil chemotaxis
positive regulation of thymocyte migration
positive regulation of natural killer cell chemotaxis
positive regulation of granzyme A production
negative regulation of T-helper 1 cell activation
positive regulation of B cell chemotaxis
positive regulation of T-helper 2 cell cytokine production
positive regulation of T-helper 1 cell cytokine production
positive regulation of immunoglobulin production in mucosal tissue
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

chemokine activity
chemokine receptor binding
protein homodimerization activity
CCR chemokine receptor binding