s128177

• Gene Symbol: Pdgfrb
• Gene Name: platelet derived growth factor receptor, beta polypeptide
• Gene Aliases: PDGFR-1
• Chromosome Location: Chr.18: 56364587 - 56406381 on Build Rnor_6.0
• UniGene ID: Rn.98311
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdgfrb
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031525.1	NP_113713.1	21	3258
	XM_006254789.2	XP_006254851.1	21	3348
	XM_008772084.1	XP_008770306.1	20	2899
GenBank mRNA	AF359356.1	-	11	1311
	AY090783.1	-	21	3258
	DQ979389.1	-	15	1997

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008809, NM_001146268, DQ979390, AK158145, AK134785, and others.

Gene Ontology Categories:

Process(es)

in utero embryonic development
kidney development
tissue homeostasis
glycosaminoglycan biosynthetic process
nitrogen compound metabolic process
signal transduction
positive regulation of cell proliferation
response to toxic substance
positive regulation of phospholipase C activity
positive regulation of phosphatidylinositol 3-kinase signaling
response to organic cyclic compound
positive regulation of smooth muscle cell migration
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
hemopoiesis
adrenal gland development
positive regulation of cell migration
response to estradiol
positive regulation of phosphoprotein phosphatase activity
response to retinoic acid
regulation of actin cytoskeleton organization
positive regulation of collagen biosynthetic process
response to lipid
response to fluid shear stress
cell migration involved in vasculogenesis
intracellular signal transduction
metanephric mesenchymal cell migration
platelet-derived growth factor receptor-beta signaling pathway
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
aorta morphogenesis
cellular response to platelet-derived growth factor stimulus
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
wound healing
response to hydrogen peroxide
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of mitotic nuclear division
phosphatidylinositol metabolic process
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
skeletal system morphogenesis
smooth muscle tissue development
inner ear development
regulation of peptidyl-tyrosine phosphorylation
positive regulation of chemotaxis
cardiac myofibril assembly
response to hyperoxia
cell chemotaxis
cell migration involved in coronary angiogenesis
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
smooth muscle cell chemotaxis
metanephric mesenchyme development
metanephric glomerular mesangial cell proliferation involved in metanephros development
metanephric glomerulus morphogenesis
metanephric glomerular capillary formation
metanephric comma-shaped body morphogenesis
metanephric S-shaped body morphogenesis
positive regulation of calcium ion import
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

protein kinase activity
protein tyrosine kinase activity
signal transducer activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
kinase activity
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
platelet-derived growth factor binding