s136958

• Gene Symbol: Nol3
• Gene Name: nucleolar protein 3 (apoptosis repressor with CARD domain)
• Gene Aliases: Arc
• Chromosome Location: Chr.19: 37232482 - 37236683 on Build Rnor_6.0
• UniGene ID: Rn.86956
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nol3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053516.2	NP_445968.2	1	126
	XM_006255539.2	XP_006255601.1	2	257
	XM_006255542.2	XP_006255604.1	2	257
	XM_008772540.1	XP_008770762.1	2	738
GenBank mRNA	U40627.1	-	1	126

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_030152, AY459322, BC053971, BC027290, AK021023, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
blood vessel remodeling
response to ischemia
mRNA splice site selection
mRNA processing
RNA splicing
regulation of gene expression
cardiac muscle cell apoptotic process
negative regulation of striated muscle cell apoptotic process
negative regulation of cardiac muscle cell apoptotic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
negative regulation of muscle atrophy
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
response to injury involved in regulation of muscle adaptation
regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
myoblast differentiation
smooth muscle cell proliferation
protein oligomerization
negative regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial calcium ion concentration
cellular response to hypoxia
negative regulation of release of cytochrome c from mitochondria
intrinsic apoptotic signaling pathway
inhibition of cysteine-type endopeptidase activity
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of mitochondrial membrane permeability involved in apoptotic process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of death-inducing signaling complex assembly
negative regulation of hydrogen peroxide-induced cell death
negative regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

receptor binding
calcium ion binding
protein binding
kinase binding
phosphatase binding
death effector domain binding
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
caspase binding