s13983 Validated

• Gene Symbol: TEK
• Gene Name: TEK receptor tyrosine kinase
• Gene Aliases: CD202B, TIE-2, TIE2, VMCM, VMCM1
• Chromosome Location: Chr.9: 27109141 - 27230178 on Build GRCh38
• UniGene ID: Hs.89640
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TEK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000459.4	NP_000450.2	10	1899
	NM_001290077.1	NP_001277006.1	9	1770
	NM_001290078.1	NP_001277007.1	8	1458
	XM_005251561.1	XP_005251618.1	10	1566
	XM_005251563.1	XP_005251620.1	9	1437
GenBank mRNA	AB086825.1	-	9	1426
	AB208796.1	-	10	1577
	AK291775.1	-	10	1587
	AK294887.1	-	8	1459
	AK295043.1	-	9	1496
	AK308447.1	-	7	1010
	BC035514.1	-	10	1574	5228999
	EU826592.1	-	9	1320
	L06139.1	-	10	1597

More Information

Matching Taqman Gene Expression Assay:

Hs00176096_m1

Gene Ontology Categories:

Process(es)

MAPK cascade
angiogenesis
response to hypoxia
positive regulation of protein phosphorylation
endothelial cell proliferation
positive regulation of endothelial cell proliferation
endochondral ossification
sprouting angiogenesis
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
heart development
positive regulation of endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
organ regeneration
regulation of establishment or maintenance of cell polarity
substrate adhesion-dependent cell spreading
negative regulation of apoptotic process
regulation of vascular permeability
response to peptide hormone
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of angiogenesis
protein autophosphorylation
Tie signaling pathway
negative regulation of inflammatory response
leukocyte migration
protein oligomerization
response to cAMP
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
definitive hemopoiesis
heart trabecula formation
positive regulation of ERK1 and ERK2 cascade
positive regulation of intracellular signal transduction
positive regulation of actin cytoskeleton reorganization
regulation of endothelial cell apoptotic process
negative regulation of endothelial cell apoptotic process

Function(s)

protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
growth factor binding