s14341 Validated

• Gene Symbol: TPM1
• Gene Name: tropomyosin 1 (alpha)
• Gene Aliases: C15orf13, CMD1Y, CMH3, HEL-S-265, HTM-alpha, LVNC9, TMSA
• Chromosome Location: Chr.15: 63042196 - 63071915 on Build GRCh38
• UniGene ID: Hs.133892
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000366.5	NP_000357.3	8	954
	NM_001018004.1	NP_001018004.1	8	954
	NM_001018005.1	NP_001018005.1	8	954
	NM_001018006.1	NP_001018006.1	8	954
	NM_001018007.1	NP_001018007.1	8	954
	NM_001018008.1	NP_001018008.1	7	794
	NM_001018020.1	NP_001018020.1	8	954
	NM_001301244.1	NP_001288173.1	8	954
	NM_001301289.1	NP_001288218.1	7	794
	XM_005254637.1	XP_005254694.1	9	1035
	XM_005254638.3	XP_005254695.2	8	1397
	XM_005254639.3	XP_005254696.2	8	1397
	XM_005254645.2	XP_005254702.2	8	1397
	XM_005254647.3	XP_005254704.1	7	780
	XM_005254650.3	XP_005254707.1	7	780
	XM_005254651.1	XP_005254708.1	7	780
	XM_005254652.1	XP_005254709.1	7	780
	XM_005254653.2	XP_005254710.1	7	780
	XM_006720667.3	XP_006720730.2	8	1397
	XM_017022538.1	XP_016878027.1	8	1397
	XM_017022539.1	XP_016878028.1	8	1397
	XM_017022541.1	XP_016878030.1	7	780
GenBank mRNA	AB209041.1	-	7	831
	AF474156.1	-	7	556
	AJ000147.1	-	1	55
	AJ001055.1	-	1	55
	AK057989.1	-	10	740
	AK092051.1	-	6	2612
	AK092573.1	-	7	1852
	AK129882.1	-	7	641
	AK131384.1	-	9	968
	AK299387.1	-	8	843
	AK301319.1	-	7	690
	AL050179.1	-	8	835
	AY640414.1	-	8	763
	AY640415.1	-	8	763
	BC007433.2	-	8	904	2962925
	BC050473.1	-	7	781
	BC053545.1	-	7	792	5730451
	BX458841.2	-	8	823
	CD679271.1	-	4	285
	DQ424903.1	-	7	655
	GQ472198.1	-	8	904
	KU178366.1	-	8	763
	KU178367.1	-	8	763
	M19713.1	-	8	819
	M19714.1	-	8	705
	M19715.1	-	7	600
	X12369.1	-	7	593
	Z24727.1	-		978

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001301336, NM_001301736, NM_001034070, NM_001034068, NM_019131, and others.
This siRNA also targets the following transcripts in Mouse: NM_001164255, NM_001164254, NM_001164256, NM_001164250, NM_024427, and others.

Matching Taqman Gene Expression Assay:

Hs00165966_m1

Gene Ontology Categories:

Process(es)

in utero embryonic development
positive regulation of heart rate by epinephrine
movement of cell or subcellular component
muscle contraction
regulation of muscle contraction
cytoskeleton organization
regulation of heart contraction
regulation of cell shape
muscle filament sliding
negative regulation of cell migration
ruffle organization
positive regulation of ATPase activity
cellular response to reactive oxygen species
wound healing
sarcomere organization
positive regulation of cell adhesion
positive regulation of stress fiber assembly
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration

Function(s)

actin binding
structural constituent of cytoskeleton
protein binding
cytoskeletal protein binding
structural constituent of muscle