s165477

• Gene Symbol: Tlr9
• Gene Name: toll-like receptor 9
• Gene Aliases: -
• Chromosome Location: Chr.8: 114916122 - 114920171 on Build Rnor_6.0
• UniGene ID: Rn.92495
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tlr9
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_198131.1	NP_937764.1	2	1549
GenBank mRNA	AY191271.1	-	2	1549

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_031178, AF348140, AB045181, AF314224.

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
immune response
I-kappaB phosphorylation
male gonad development
response to virus
positive regulation of autophagy
maintenance of gastrointestinal epithelium
negative regulation of NF-kappaB transcription factor activity
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
positive regulation of toll-like receptor signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
regulation of cytokine secretion
regulation of inflammatory response
positive regulation of inflammatory response
defense response to Gram-negative bacterium
regulation of B cell activation
positive regulation of NF-kappaB transcription factor activity
defense response to virus
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to metal ion

Function(s)

transmembrane signaling receptor activity
interleukin-1 receptor binding
siRNA binding
unmethylated CpG binding