s16962

• Gene Symbol: SQSTM1
• Gene Name: sequestosome 1
• Gene Aliases: A170, FTDALS3, OSIL, PDB3, ZIP3, p60, p62, p62B
• Chromosome Location: Chr.5: 179806388 - 179838078 on Build GRCh38
• UniGene ID: Hs.587290
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SQSTM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001142298.1	NP_001135770.1	3	398
	NM_001142299.1	NP_001135771.1	3	315
	NM_003900.4	NP_003891.1	2	385
	XM_017010010.1	XP_016865499.1	2	617
GenBank mRNA	AK025146.1	-	2	104
	AK098077.1	-	1	558
	AK226167.1	-	2	107
	AK293509.1	-	2	322
	AK304877.1	-	2	322
	AK312451.1	-	2	349
	BC000951.2	-	1	74
	BC001874.1	-	4	549	3535436
	BC003139.1	-	2	308	2906264
	BC005857.2	-	1	48
	BC017222.1	-	2	330	4298142
	BC019111.1	-	2	322	5091391
	BI549805.1	-	3	403
	BM800056.1	-		336
	DA541885.1	-	3	315
	DC398116.1	-	2	385
	U41806.1	-	2	310
	U46751.1	-	2	342

More Information

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
immune system process
protein phosphorylation
ubiquitin-dependent protein catabolic process
autophagy
apoptotic process
response to stress
protein localization
regulation of mitochondrion organization
endosomal transport
macroautophagy
positive regulation of macroautophagy
cell differentiation
intracellular signal transduction
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
protein heterooligomerization
regulation of protein complex stability
mitophagy in response to mitochondrial depolarization

Function(s)

protein serine/threonine kinase activity
protein kinase C binding
protein binding
zinc ion binding
protein kinase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
SH2 domain binding
identical protein binding
protein homodimerization activity
ubiquitin binding
K63-linked polyubiquitin binding