s176002

• Gene Symbol: Eng
• Gene Name: endoglin
• Gene Aliases: -
• Chromosome Location: Chr.3: 11679530 - 11717485 on Build Rnor_6.0
• UniGene ID: Rn.187025
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Eng
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001010968.2	NP_001010968.1	7	1112
GenBank mRNA	AY562420.1	-	7	825
	BC105860.1	-	7	1112	7456529

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chronological cell aging
angiogenesis
patterning of blood vessels
vasculogenesis
response to hypoxia
positive regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
heart looping
positive regulation of systemic arterial blood pressure
cell migration involved in endocardial cushion formation
regulation of transcription, DNA-templated
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
heart development
positive regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
cell migration
regulation of transforming growth factor beta receptor signaling pathway
central nervous system vasculogenesis
extracellular matrix disassembly
negative regulation of cell migration
positive regulation of BMP signaling pathway
negative regulation of protein autophosphorylation
response to corticosteroid
positive regulation of collagen biosynthetic process
intracellular signal transduction
response to statin
wound healing
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
smooth muscle tissue development
artery morphogenesis
venous blood vessel morphogenesis
cell motility
negative regulation of nitric-oxide synthase activity
cell chemotaxis
bone development
negative regulation of pathway-restricted SMAD protein phosphorylation
extracellular matrix constituent secretion
detection of hypoxia
cellular response to mechanical stimulus
response to transforming growth factor beta

Function(s)

transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor, cytoplasmic mediator activity
type II transforming growth factor beta receptor binding
galactose binding
glycosaminoglycan binding
type I transforming growth factor beta receptor binding
BMP binding
protein homodimerization activity
transforming growth factor beta binding