s176052

• Gene Symbol: Brca1
• Gene Name: breast cancer 1, early onset
• Gene Aliases: -
• Chromosome Location: Chr.10: 89394821 - 89455009 on Build Rnor_6.0
• UniGene ID: Rn.217584
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Brca1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012514.1	NP_036646.1	10	1172
	XM_008768092.1	XP_008766314.1	10	1388
GenBank mRNA	AF036760.1	-	10	1172
	AF234782.1	-	1	228

More Information

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
DNA replication
postreplication repair
double-strand break repair
regulation of gene expression by genetic imprinting
fatty acid biosynthetic process
cellular response to DNA damage stimulus
chromosome segregation
centrosome cycle
brain development
response to nutrient
intrinsic apoptotic signaling pathway in response to DNA damage
dosage compensation by inactivation of X chromosome
response to organic substance
response to ionizing radiation
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
protein ubiquitination
positive regulation of protein ubiquitination
response to estradiol
response to lipid
positive regulation of histone acetylation
negative regulation of histone acetylation
regulation of cell proliferation
chordate embryonic development
response to estrogen
regulation of DNA methylation
negative regulation of fatty acid biosynthetic process
positive regulation of DNA repair
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
positive regulation of histone H3-K9 methylation
protein autoubiquitination
positive regulation of histone H4-K20 methylation
positive regulation of cell cycle arrest
cellular response to tumor necrosis factor
cellular response to indole-3-methanol
protein K6-linked ubiquitination
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of cell motility
negative regulation of reactive oxygen species metabolic process
positive regulation of histone H3-K9 acetylation
positive regulation of histone H4-K16 acetylation

Function(s)

DNA binding
damaged DNA binding
RNA binding
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
enzyme binding
ubiquitin protein ligase binding
transcription regulatory region DNA binding