s1880 Validated

• Gene Symbol: BAK1
• Gene Name: BCL2 antagonist/killer 1
• Gene Aliases: BAK, BAK-LIKE, BCL2L7, CDN1
• Chromosome Location: Chr.6: 33572546 - 33580293 on Build GRCh38
• UniGene ID: Hs.485139
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BAK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001188.3	NP_001179.1	3	407
	XM_011514779.2	XP_011513081.1	4	518
GenBank mRNA	AF520590.1	-	2	107
	AK292093.1	-	4	445
	AK293547.1	-	3	337
	AK303422.1	-	3	386
	BC004431.1	-	1	318	2819507
	BC110337.1	-	3	317	5755200
	CB142221.1	-	3	407
	CR457419.1	-	2	107
	KU177934.1	-	2	107
	KU177935.1	-	2	107
	U16811.1	-	3	307
	U23765.1	-	3	171
	X84213.1	-	3	299

More Information

Matching Taqman Gene Expression Assay:

Hs00832876_g1

Gene Ontology Categories:

Process(es)

B cell homeostasis
B cell apoptotic process
release of cytochrome c from mitochondria
blood vessel remodeling
myeloid cell homeostasis
B cell negative selection
activation of signaling protein activity involved in unfolded protein response
brain development
aging
mitochondrial fusion
cell proliferation
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
response to fungus
response to mycotoxin
response to UV-C
establishment or maintenance of transmembrane electrochemical gradient
response to gamma radiation
positive regulation of calcium ion transport into cytosol
negative regulation of gene expression
response to organic cyclic compound
cytolysis
endocrine pancreas development
organ regeneration
endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum calcium ion concentration
negative regulation of peptidyl-serine phosphorylation
cellular response to UV
limb morphogenesis
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
fibroblast apoptotic process
response to ethanol
positive regulation of proteolysis
regulation of mitochondrial membrane permeability
post-embryonic camera-type eye morphogenesis
regulation of cell cycle
regulation of mitochondrial membrane potential
vagina development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
thymocyte apoptotic process
cellular response to mechanical stimulus
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
positive regulation of endoplasmic reticulum unfolded protein response
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
apoptotic process involved in patterning of blood vessels
positive regulation of IRE1-mediated unfolded protein response

Function(s)

protein binding
heat shock protein binding
identical protein binding
protein homodimerization activity
ion channel binding
metal ion binding
protein heterodimerization activity
chaperone binding
BH domain binding