s201386

• Gene Symbol: Gch1
• Gene Name: GTP cyclohydrolase 1
• Gene Aliases: GTP-CH, GTPCH, Gch
• Chromosome Location: Chr.14: 47153895 - 47189402 on Build GRCm38
• UniGene ID: Mm.10651
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gch1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008102.3	NP_032128.1	2	496
GenBank mRNA	AK150657.1	-	2	508
	AK152571.1	-	2	508
	BC005643.1	-	2	496	3709238
	BC069921.1	-	2	500	6529016
	L09737.1	-	2	483
	S71373.1	-	2	213

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_024356, M58364, FQ220953.

Gene Ontology Categories:

Process(es)

protein complex assembly
tetrahydrobiopterin biosynthetic process
metabolic process
regulation of blood pressure
regulation of lung blood pressure
response to interferon-gamma
response to tumor necrosis factor
vasodilation
dopamine biosynthetic process
pteridine-containing compound biosynthetic process
negative regulation of blood pressure
tetrahydrofolate biosynthetic process
response to pain
neuromuscular process controlling posture
positive regulation of nitric-oxide synthase activity
dihydrobiopterin metabolic process
protein homooligomerization
protein heterooligomerization

Function(s)

nucleotide binding
catalytic activity
GTP cyclohydrolase I activity
calcium ion binding
GTP binding
zinc ion binding
hydrolase activity
GTP-dependent protein binding
protein homodimerization activity
metal ion binding
coenzyme binding