s201736

• Gene Symbol: Npm1
• Gene Name: nucleophosmin 1
• Gene Aliases: B23, NO38, Npm
• Chromosome Location: Chr.11: 33152498 - 33163206 on Build GRCm38
• UniGene ID: Mm.485384
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Npm1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001252260.1	NP_001239189.1	9	909
	NM_001252261.1	NP_001239190.1	9	948
	NM_008722.3	NP_032748.1	9	948
GenBank mRNA	AK005420.1	-	9	819
	AK005498.1	-	9	818
	AK028253.1	-	9	819
	AK088923.1	-	9	818
	AK135517.1	-	9	819
	AK145124.1	-	9	818
	AK145813.1	-	9	819
	AK165860.1	-	9	820
	AK184065.1	-	1	61
	BC054755.1	-	9	801	6411700
	BC085278.1	-	9	779	30438901
	BC089546.1	-	9	818	30505980
	BC090843.1	-	9	801	6820557
	BC092378.1	-	9	783	5710278
	BU513690.1	-	9	766
	CX567338.1	-	4	233
	GU214027.1	-	9	822
	M33212.1	-	9	799

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002520, NM_199185, NM_001037738, BC016716, AY740635, and others.

Gene Ontology Categories:

Process(es)

ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
DNA repair
nucleosome assembly
rRNA export from nucleus
cell volume homeostasis
nucleocytoplasmic transport
response to stress
centrosome cycle
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
regulation of centrosome duplication
positive regulation of centrosome duplication
negative regulation of centrosome duplication
cell growth
positive regulation of cellular biosynthetic process
protein destabilization
regulation of endodeoxyribonuclease activity
ribosomal large subunit biogenesis
ribosomal small subunit biogenesis
negative regulation of apoptotic process
positive regulation of catalytic activity
regulation of DNA damage response, signal transduction by p53 class mediator
regulation of neuron apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of DNA replication
positive regulation of protein kinase activity
regulation of centriole replication
negative regulation of mRNA splicing, via spliceosome
positive regulation of DNA metabolic process
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
protein homooligomerization
regulation of cell cycle
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA

Function(s)

nucleic acid binding
DNA binding
transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
phosphatidylinositol-3,4,5-trisphosphate binding
rRNA binding
enzyme binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
protein N-terminus binding
NF-kappaB binding
unfolded protein binding