s20966

• Gene Symbol: CTCF
• Gene Name: CCCTC-binding factor
• Gene Aliases: MRD21
• Chromosome Location: Chr.16: 67562407 - 67639185 on Build GRCh38
• UniGene ID: Hs.368367
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CTCF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001191022.1	NP_001177951.1	4	598
	NM_006565.3	NP_006556.1	6	1559
	XM_005255775.3	XP_005255832.1	6	1559
	XM_017022868.1	XP_016878357.1	6	1309
	XM_017022869.1	XP_016878358.1	6	1308
GenBank mRNA	AB209793.1	-	4	432
	AK314804.1	-	6	1557
	BC014267.2	-	6	1393	3840827
	BT009915.1	-	4	1115
	U25435.1	-	6	1406

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031824, XM_008772537, XM_006255536, XM_008772539, XM_008772536, and others.
This siRNA also targets the following transcripts in Mouse: NM_181322, U51037, BC058240, BC046398, AK132514, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
regulation of gene expression by genetic imprinting
transcription from RNA polymerase II promoter
chromosome segregation
maintenance of DNA methylation
positive regulation of gene expression
covalent chromatin modification
nucleosome positioning
regulation of histone methylation
regulation of histone acetylation
regulation of gene expression, epigenetic
regulation of molecular function, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of centromeric sister chromatid cohesion

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
zinc ion binding
chromatin insulator sequence binding
sequence-specific DNA binding
transcription regulatory region DNA binding