s2168

Gene Symbol:

C4A C4B C4B_2

Gene Name:

complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)

complement component 4B (Chido blood group), copy 2

Gene Aliases:

C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG

C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3

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Chromosome Location:

Chr.6: 31982057 - 32002680 on Build GRCh38

Chromosome Location:

Chr.6: 32014795 - 32035418 on Build GRCh38

Chromosome Location:

-

UniGene ID:

Hs.534847

Hs.534847

Hs.720022

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: C4A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001252204.1	NP_001239133.1	37, 38	4796
	NM_007293.2	NP_009224.2	38, 39	4934
GenBank mRNA	AB209989.1	-	38, 39	4923
	AK293191.1	-	13, 14	1579
	BC012372.2	-	3, 4	257
	BC063289.1	-	38, 39	4967	5289068
	BC144546.1	-	38, 39	4904	9053073
	BC146673.1	-	37, 38	4785	40148477
	BC146849.1	-	38, 39	4904	9056777
	BC151204.1	-	38, 39	4921	40147083
	BC171786.1	-	38, 39	4904	9054440
	K02403.1	-	38, 39	4914
	S81585.1	-	3, 4	354

Gene Symbol: C4B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001002029.3	NP_001002029.3	38, 39	4934
GenBank mRNA	AK304564.1	-	17, 18	2049

Gene Symbol: C4B_2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001242823.2	NP_001229752.1	38, 39	4934

More Information

Gene Ontology Categories:

Process(es)

proteolysis
inflammatory response
complement activation
complement activation, classical pathway
negative regulation of endopeptidase activity
regulation of complement activation
innate immune response
positive regulation of apoptotic cell clearance
opsonization
detection of molecule of bacterial origin

Function(s)

complement component C1q binding
serine-type endopeptidase activity
endopeptidase inhibitor activity
complement binding
carbohydrate binding