s219791

• Gene Symbol: Htt
• Gene Name: huntingtin
• Gene Aliases: Hd, Hdh
• Chromosome Location: Chr.14: 81105139 - 81254637 on Build Rnor_6.0
• UniGene ID: Rn.11193
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Htt
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024357.3	NP_077333.2	48	6570
	XM_006251230.2	XP_006251292.1	47	6508
	XM_006251232.2	XP_006251294.1	48	6556
	XM_008770274.1	XP_008768496.1	46	6022

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010414, L23312, L28827, L23313, AK084575, and others.

Gene Ontology Categories:

Process(es)

urea cycle
citrulline metabolic process
establishment of mitotic spindle orientation
protein import into nucleus
mitochondrial transport
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
apoptotic process
mitochondrion organization
endoplasmic reticulum organization
Golgi organization
dopamine receptor signaling pathway
spermatogenesis
gastrulation
central nervous system development
brain development
cell aging
learning or memory
learning
grooming behavior
locomotory behavior
axo-dendritic transport
associative learning
determination of adult lifespan
visual learning
anatomical structure morphogenesis
anterior/posterior pattern specification
endosomal transport
lactate biosynthetic process from pyruvate
quinolinate biosynthetic process
striatum development
olfactory lobe development
neural plate formation
neurogenesis
peptide hormone secretion
insulin secretion
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
regulation of protein phosphatase type 2A activity
social behavior
hormone metabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
regulation of mitochondrial membrane permeability
vesicle transport along microtubule
regulation of synaptic plasticity
paraxial mesoderm formation
animal organ development
neuron development
mRNA transport
neuron apoptotic process
response to calcium ion
regulation of mitochondrial membrane potential
L-glutamate import
iron ion homeostasis
negative regulation of neuron death
negative regulation of cysteine-type endopeptidase activity
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

p53 binding
receptor binding
protein binding
transcription factor binding
dynactin binding
identical protein binding
ion channel binding
dynein intermediate chain binding
beta-tubulin binding
diazepam binding