s230718

• Gene Symbol: DMTN
• Gene Name: dematin actin binding protein
• Gene Aliases: DMT, EPB49
• Chromosome Location: Chr.8: 22048955 - 22082527 on Build GRCh38
• UniGene ID: Hs.106124
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DMTN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001114135.4	NP_001107607.1	10	1027
	NM_001114136.2	NP_001107608.1	10	983
	NM_001114137.3	NP_001107609.1	10	1157
	NM_001114138.2	NP_001107610.1	10	1144
	NM_001114139.3	NP_001107611.1	9	1041
	NM_001302816.2	NP_001289745.1	10	1277
	NM_001302817.2	NP_001289746.1	8	996
	NM_001323378.1	NP_001310307.1	10	1116
	NM_001323380.1	NP_001310309.1	10	1023
	NM_001323381.1	NP_001310310.1	9	1132
	NM_001323382.1	NP_001310311.1	10	1062
	NM_001323383.1	NP_001310312.1	10	983
	NM_001323384.1	NP_001310313.1	10	1116
	NM_001323385.1	NP_001310314.1	9	1132
	NM_001323387.1	NP_001310316.1	9	1081
	NM_001323388.1	NP_001310317.1	8	863
	NM_001323389.1	NP_001310318.1	9	1071
	NM_001323390.1	NP_001310319.1	9	938
	NM_001323391.1	NP_001310320.1	9	1041
	NM_001323392.1	NP_001310321.1	9	1202
	NM_001323393.1	NP_001310322.1	9	908
	NM_001323394.1	NP_001310323.1	9	1069
	NM_001323395.1	NP_001310324.1	9	948
	NM_001323396.1	NP_001310325.1	9	952
	NM_001323397.1	NP_001310326.1	9	1120
	NM_001323398.1	NP_001310327.1	8	996
	NM_001323399.1	NP_001310328.1	8	863
	NM_001323400.1	NP_001310329.1	7	1012
	NM_001323401.1	NP_001310330.1	8	1036
	NM_001978.4	NP_001969.2	10	1277
	XM_005273432.1	XP_005273489.1	10	1009
	XM_005273433.1	XP_005273490.1	10	941
	XM_005273442.1	XP_005273499.1	9	793
	XM_011544435.1	XP_011542737.1	9	1202
	XM_017013189.1	XP_016868678.1	10	950
	XM_017013190.1	XP_016868679.1	9	1202
	XM_017013191.1	XP_016868680.1	9	956
	XM_017013192.1	XP_016868681.1	9	837
	XM_017013193.1	XP_016868682.1	8	969
	XM_017013194.1	XP_016868683.1	8	836
	XM_017013195.1	XP_016868684.1	9	1202
	XM_017013196.1	XP_016868685.1	9	805
	XM_017013197.1	XP_016868686.1	9	1036
	XM_017013198.1	XP_016868687.1	9	878
GenBank mRNA	AB209718.1	-	6	503
	AK055842.1	-	10	941
	AK091581.1	-	9	956
	AK289650.1	-	10	909
	AK295452.1	-	8	882
	BC006318.2	-	10	1026	4125804
	BC017445.1	-	10	1026	3162732
	BC052805.1	-	10	1067	6269658
	BT007396.1	-	9	754
	L19713.1	-	10	1204
	U28389.1	-	10	1204

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108385, XM_008770831, XM_006252279, XM_006252281, XM_008770830, and others.
This siRNA also targets the following transcripts in Mouse: NM_013514, NM_001252666, NM_001252665, NM_001252662, NM_001252663, and others.

Gene Ontology Categories:

Process(es)

protein complex assembly
cytoskeleton organization
regulation of cell shape
regulation of lamellipodium assembly
positive regulation of fibroblast migration
negative regulation of peptidyl-threonine phosphorylation
negative regulation of cell-substrate adhesion
actin cytoskeleton organization
positive regulation of blood coagulation
regulation of actin cytoskeleton organization
negative regulation of peptidyl-serine phosphorylation
calcium-mediated signaling using intracellular calcium source
calcium-mediated signaling using extracellular calcium source
erythrocyte development
negative regulation of peptidyl-tyrosine phosphorylation
actin filament bundle assembly
regulation of filopodium assembly
actin filament capping
negative regulation of focal adhesion assembly
transmembrane transport
protein secretion by platelet
cellular response to calcium ion
cellular response to cAMP
positive regulation of wound healing
negative regulation of protein targeting to membrane
actin filament reorganization
negative regulation of substrate adhesion-dependent cell spreading
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of platelet aggregation
positive regulation of integrin-mediated signaling pathway

Function(s)

actin binding
receptor binding
protein binding
spectrin binding