s231302

• Gene Symbol: DNMT3A
• Gene Name: DNA methyltransferase 3 alpha
• Gene Aliases: DNMT3A2, M.HsaIIIA, TBRS
• Chromosome Location: Chr.2: 25232961 - 25342590 on Build GRCh38
• UniGene ID: Hs.515840
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNMT3A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320892.1	NP_001307821.1	2	165
	NM_022552.4	NP_072046.2	2	165
	NM_175629.2	NP_783328.1	2	236
	NM_175630.1	NP_783329.1	2	236
	NR_135490.1		2	236
	XM_005264175.4	XP_005264232.1	2	99
	XM_011532663.2	XP_011530965.1	2	175
	XM_011532664.2	XP_011530966.1	2	176
	XM_017003526.1	XP_016859015.1	2	207
GenBank mRNA	AB208833.1	-	2	135
	AF067972.2	-	2	127
	AF331856.1	-	2	115
	AL543971.3	-	2	165
	BC032392.1	-	2	236
	BC043617.1	-	2	135	6150112
	BC051864.1	-	2	104

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
spermatogenesis
aging
response to toxic substance
response to ionizing radiation
response to lead ion
DNA methylation on cytosine within a CG sequence
positive regulation of cell death
neuron differentiation
response to estradiol
response to vitamin A
response to antidepressant
response to cocaine
DNA methylation involved in embryo development
DNA methylation involved in gamete generation
hypermethylation of CpG island
negative regulation of gene expression, epigenetic
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
cellular response to amino acid stimulus
cellular response to ethanol
cellular response to hypoxia
C-5 methylation of cytosine
hepatocyte apoptotic process

Function(s)

DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates