s27 Validated

• Gene Symbol: SREBF2
• Gene Name: sterol regulatory element binding transcription factor 2
• Gene Aliases: SREBP-2, SREBP2, bHLHd2
• Chromosome Location: Chr.22: 41833079 - 41907308 on Build GRCh38
• UniGene ID: Hs.443258
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SREBF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004599.3	NP_004590.2	15	2885
	NR_103834.1		16	2985
	XM_006724310.2	XP_006724373.1	15	3129
	XM_011530347.1	XP_011528649.1	13	2339
	XM_017028921.1	XP_016884410.1	15	2714
GenBank mRNA	AK299914.1	-	15	2714
	AL834221.1	-	7	1244
	BC051385.1	-	16	2891	5497929
	BC051799.1	-	15	2851
	BC056158.1	-	15	2831	6169568
	CT841522.1	-	15	2775
	U02031.1	-	15	2810

More Information

Matching Taqman Gene Expression Assay:

Hs00190237_m1

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
lipid metabolic process
cholesterol metabolic process
cellular response to starvation
positive regulation of cholesterol storage
positive regulation of transcription from RNA polymerase II promoter
response to low-density lipoprotein particle
cellular response to laminar fluid shear stress
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of cholesterol homeostasis

Function(s)

C-8 sterol isomerase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
protein C-terminus binding
protein dimerization activity
E-box binding